Pepe's Cantina Mexican Grill will soon bring its specialty margaritas, authentic Mexican cuisine, and fresh tableside guacamole to St. Pete's Kenwood neighborhood.

The expanding Central Florida-based franchise is opening its first Tampa Bay location at 3118 3rd Avenue North in the Shoppes at Kenwood.

The 2,275-square-foot space was previously home to the Cider Press Vegan GastroPub, which closed in October 2024, and before that, it housed the iconic LGBT bar Georgie’s Alibi.