Orlando Health completes Institute Square, a new medical campus next to Bayfront Hospital in downtown St. Pete

Orlando Health’s three-story, 60,000-square-foot Women’s Pavilion at 570 8th Street South in downtown St. Pete | St. Pete Rising

Orlando Health has completed construction on Institute Square, a new medical campus just north of its 480-bed Bayfront Hospital in downtown St. Petersburg’s Innovation District.

The development spans an entire city block bounded by 5th Avenue South, 6th Avenue South, 7th Street South, and 8th Street South.

It includes a four-story Orlando Health Medical Pavilion, a three-story Orlando Health Women’s Pavilion, and a five-story, 817-space parking garage that also houses an imaging center and a wound care center.

Hospital leaders are expected to formally mark the opening with a ribbon-cutting ceremony on February 12th.

Construction on the project began in late 2023, led by Turner Construction Company. Orlando-based construction firm Finfrock built the parking garage.

Site plan for Orlando Health’s Institute Square in downtown St. pete | St Pete Rising

The largest building on the site is the four-story, 132,000-square-foot Medical Pavilion at 725 6th Avenue South. The facility houses a range of outpatient services, including cancer care, orthopedics, and surgical specialties.

Anchoring the building is the Neuroscience Institute, which consolidates Bayfront Hospital’s Level 4 Epilepsy Center and Comprehensive Stroke Center.

The institute includes expanded staffing and a neuro ICU, along with advanced 3D imaging systems, digital technologies, and clot-removal tools designed to support complex neurological care.

The Medical Pavilion is also home to the Florida Cancer Specialists and Research Institute, the nation’s largest independent oncology and hematology group.

The practice operates nearly 100 locations across Florida and employs more than 250 physicians. At Institute Square, specialists provide treatment for a range of cancers, including breast, colorectal, thoracic, lung, head and neck, skin, and urogynecologic cancers.

Orlando Health’s four-story, 132,000-square-foot Medical Pavilion at 725 6th Avenue South in downtown St. Pete | St. PEte Rising

Orlando Health’s surgical oncology department also operates out of the pavilion, Bayfront Hospital President John Moore said during a January 15 City Council meeting.

Additionally, the Orlando Health Jewett Orthopedic Institute occupies space in the Medical Pavilion.

The institute provides orthopedic and sports medicine services, treating conditions involving the spine as well as the upper and lower extremities.

Care teams include specialists in neurosurgery, musculoskeletal radiology, anesthesia, interventional pain management, and hospital-based internal medicine, with expertise in joint replacement, concussions, bone health, and orthopedic trauma.

West of the Medical Pavilion is the three-story, 60,000-square-foot Women’s Pavilion at 570 8th Street South.

The facility, which is operated in partnership with Women’s Care, focuses on obstetrics, gynecology, and women’s health services spanning all stages of life.

An Orlando Health imaging center and wound care center are located on the first floor of the new parking garage | St. Pete Rising

It also houses Orlando Health’s OB-GYN residency program and a fertility clinic, with additional services planned for the upper floors.

On the north side of the campus is the five-level parking garage, which includes an Outpatient Wound Healing Center at 710 5th Avenue South and an Orlando Health Imaging Center at 540 8th Street South.

The Imaging Center offers a full range of diagnostic services, including 3T MRI, CT scans, Doppler ultrasound, mammography, PET/CT exams, DEXA scans, and X-rays.

The Wound Healing Center is equipped with hyperbaric chambers designed to increase oxygen delivery to damaged tissue and support recovery.

The opening of Institute Square marks another milestone in Bayfront Hospital’s turnaround since Orlando Health acquired the facility from Community Health Systems in 2020.

At the time of the acquisition, Orlando Health pledged to stabilize and reinvest in the hospital following years of operational challenges.

Since then, the hospital has expanded its physician staff, strengthened charity care programs, and improved its Leapfrog Hospital Safety Grade from a D to an A.